A bacteriophage-like particle from Bartonella bacilliformis

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Isolation and characterization of Bartonella bacilliformis from an expatriate Ecuadorian.

Carrion's disease is typically biphasic with acute febrile illness characterized by bacteremia and severe hemolytic anemia (Oroya fever), followed by benign, chronic cutaneous lesions (verruga peruana). The causative agent, Bartonella bacilliformis, is endemic in specific regions of Peru and Ecuador. We describe atypical infection in an expatriate patient who presented with acute splenomegaly a...

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Demonstration of Agglutinins for Bartonella Bacilliformis

1. Methods of preparing a satisfactory antigen having been developed, a technique for performing an agglutination test with B. bacilliformis is made available. 2. As a result of repeated intravenous injection of living cultures of B. bacilliformis at short intervals, rabbits have been found to produce a high titre of specific agglutinins which, under the conditions obtaining in the present seri...

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Development of a system for genetic manipulation of Bartonella bacilliformis.

Lack of a system for site-specific genetic manipulation has severely hindered studies on the molecular biology of all Bartonella species. We report the first site-specific mutagenesis and complementation for a Bartonella species. A highly transformable strain of B. bacilliformis, termed JB584, was isolated and found to exhibit a significant increase in transformation efficiency with the broad-h...

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Whole-Genome Sequencing of Two Bartonella bacilliformis Strains

Bartonella bacilliformis is the causative agent of Carrion's disease, a highly endemic human bartonellosis in Peru. We performed a whole-genome assembly of two B. bacilliformis strains isolated from the blood of infected patients in the acute phase of Carrion's disease from the Cusco and Piura regions in Peru.

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BACKGROUND Bartonella bacilliformis is the causative agent of Carrion's disease, a neglected illness with mortality rates of 40-85% in the absence of treatment. The lack of a diagnostic technique to overcome misdiagnosis and treat asymptomatic carriers is of note. This study aimed to identify new B. bacilliformis antigenic candidates that could lead to a new diagnostic tool able to be implement...

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ژورنال

عنوان ژورنال: Microbiology

سال: 2000

ISSN: 1350-0872,1465-2080

DOI: 10.1099/00221287-146-3-599